Invalid addresses left in the queue to which repeated attempts are made to send

How long does it try to send mail to addresses with errors, how can this be stopped and can it be defined somewhere that the addresses would be marked on a black list so that the same thing does not happen again?

Error sending email to doe.john@doe.tld SMTP Error: The following recipients failed: doe.john@doe.tld: The mail server could not deliver mail to doe.john@doe.tld. The account or domain may not exist, they may be blacklisted, or missing the proper dns entries.

When sending a campaign, bounces should be directed to the message envelope mailbox.
When using Advanced bounce rules, you can indicate how to handle a bounce by setting up rules, i.e. in your case, the rule might be ‘could not deliver’, specifying ‘add email to blacklist and delete bounce’.